Pinoy Pharmacy

Sex may not be the most important thing in life. But to most men, it’s up there. So don’t let erection problems keep you from a satisfying sex life. Learn about a condition called erectile dysfunction, or ED.

Erectile Dysfunction (ED) is when a man has problems getting or maintaining an erection long enough for sex. It happens when not enough blood flows to the penis.

ED isn’t the same for all men. Some men aren’t able to get an erection at all. Others can get one, but it’s not hard enough for sex. And others get a hard erection but lose it before or during sex.

ED is a medical condition. So in most cases, erections will not improve without treatment.

A common issue
ED is more common than you might think. More than half of all men over 40 have some difficulty getting and maintaining an erection. The fact is, guys at any age can experience ED.


Treatment options

There are many treatments for erectile dysfunction (ED). The most common is oral medication, or tablets.

Of all the ED tablets, VIAGRA is the one doctors prescribe most. It has been shown to significantly improve erections for men with ED

Sildenafil Citrate an oral medication for erectile dysfunction (ED). It helps most men with ED improve their erections. That means they are able to achieve harder erections.

Getting an erection is only half the story
Maintaining an erection is just as important as getting one. Sildenafil Citrate can help with both. This can lead to a more satisfying sexual experience with your partner.

Who can take Sildenafil Citrate
Sildenafil Citrate has an established safety profile of over 10 years. It has been shown to work safely and effectively in men with ED. This includes:

• Men of all ages
• Men who have difficulty all the time or just some of the time
• Men with other health issues such as high blood pressure, diabetes, and depression

Find out if Sildenafil is right for you. Speak to your doctor and visit your nearest Pharmacy. They can tell you if you have ED. And can recommend an effective treatment.

Most Filipino men don't visit their doctors to consult about their problem regarding Erectile Dysfunction. Instead, they buy these medication over the counter and fly-by-night pharmacies. Its is not recommended to use this drug without a consult from your medical practitioner simple because it can aggrevate other disease like heart problems.

Every pinoy pharmacist should know that Sildenafil Citrate popularly known as Vigra is a prescription drug. I shout to all pharmacist out there please do not dispense this medication without a prescription.



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Popular Brands: Valium, Novodipam, Relanium, Seduxen, Stesolid, Betapam

Diazepam is a benzodiazepine derivative. Chemically, Diazepam is 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one. It is a colorless crystalline compound, and is insoluble in water.

Mechanism of Action
Diazepam is a benzodiazepine that binds to a specific subunit on the GABAA receptor at a site that is distinct from the binding site of the endogenous GABA molecule.[19][20] The GABAA receptor is an inhibitory channel which, when activated, decreases neuronal activity.

Because of the role of diazepam as a positive allosteric modulator of GABA, when it binds to benzodiazepine receptors it causes inhibitory effects. This arises from the hyperpolarization of the post-synaptic membrane owing to the control exerted over negative chloride ions by GABAA receptors.


Side effects

* Somnolence
* Suppression of REM sleep
* Addiction
* Impaired motor function
o Impaired coordination
o Impaired balance
o Dizziness and nausea
* Depression
* Impaired learning
* Anterograde amnesia (especially pronounced in higher doses)
* Cognitive deficits
* Reflex tachycardia

Diazepam may be habit-forming and should be used only by the person it was prescribed for. This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

In the Philippines, prescription with S2 license is required before you can avail this medication.


source: drugs.com, wikipedia

Mechanism of Action
Atorvastatin is a selective, competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl-coenzyme A to mevalonate, a precursor of sterols, including cholesterol. Cholesterol and triglycerides circulate in the bloodstream as part of lipoprotein complexes. With ultracentrifugation, these complexes separate into HDL (high-density lipoprotein), IDL (intermediate-density lipoprotein), LDL (low-density lipoprotein), and VLDL (very-low-density lipoprotein) fractions. Triglycerides (TG) and cholesterol in the liver are incorporated into VLDL and released into the plasma for delivery to peripheral tissues. LDL is formed from VLDL and is catabolized primarily through the high-affinity LDL receptor. Clinical and pathologic studies show that elevated plasma levels of total cholesterol (total-C), LDL-cholesterol (LDL-C), and apolipoprotein B (apo B) promote human atherosclerosis and are risk factors for developing cardiovascular disease, while increased levels of HDL-C are associated with a decreased cardiovascular risk.


Pharmacokinetics and Drug Metabolism
Absorption: maximum plasma concentrations occur within 1 to 2 hours
Distribution: Mean volume of distribution of atorvastatin is approximately 381 liters. Atorvastatin is ≥98% bound to plasma proteins.
Metabolism: metabolized to ortho- and parahydroxylated derivatives and various beta-oxidation products
Excretion:eliminated primarily in bile following hepatic and/or extra-hepatic metabolism

Indication
1.Prevention of Cardiovascular Disease
2.Hypercholesterolemia

Adverse Effects
Muscle problems, Liver problems

Source:drugs.com

Comments: Hi! this is my first featured drug for this blog. I may not write everything from the source. I will just highlight those information i think important to us. Ang mahal ng gamot na ito. Magkano na kaya ito sa botika?